Entry 2 senses · 2 variants Webster, 1913 Tweag · IPA v. t. n. 01 v. t. To tweak. 1. To tweak.[Obs.] 02 n. A pinching condition; perplexity; trouble; distress. 1. A pinching condition; perplexity; trouble; distress.[Obs. or Prov. Eng.] “This put the old fellow in a rare tweague.” — Arbuthnot.