Entry 1 sense Webster, 1913 Significator · Sig·ni·fi·ca·tor · IPA /sɪɡˈnɪfɪˌkeɪtə(ɹ)/ 01 n. One who, or that which, signifies. 1. One who, or that which, signifies. “In this diagram there was one significator which pressed remarkably upon our astrologer's attention.” — Sir W. Scott.