Entry 1 sense Webster, 1913 Scepsis · Scep·sis · IPA /ˈskɛpsɪs/ 01 n. Skepticism; skeptical philosophy. 1. Skepticism; skeptical philosophy.[R.] “Among their products were the system of Locke, the scepsis of Hume, the critical philosophy of Kant.” — J. Martineau.