Entry 1 sense Webster, 1913 Progeny /(prŏj"ē̇*ny̆)/ · Prog·e·ny · IPA /ˈpɹɑd͡ʒəni/ 01 n. Descendants of the human kind, or offspring of other animals; children; offspring; race, lineage. 1. Descendants of the human kind, or offspring of other animals; children; offspring; race, lineage.