Entry 1 sense Webster, 1913 Preclusion /prĭk-lo͞ozh'-ən/ · Pre·clu·sion · IPA /prɪklˈuːʒən/ 01 n. The act of precluding, or the state of being precluded; a shutting out. 1. The act of precluding, or the state of being precluded; a shutting out.