Entry 1 sense Webster, 1913 Phrenic /(frĕn"ĭk)/ · Phren·ic · IPA /ˈfɹɛnɪk/ 01 a. Of or pertaining to the diaphragm; diaphragmatic; as, the phrenic nerve. 1. Of or pertaining to the diaphragm; diaphragmatic; as, the phrenic nerve.(Anat.)