Entry 1 sense Webster, 1913 nanotechnology /(năn"ō̇*tĕk*nŏl`ō̇*jē)/ · nan·o·tech·nol·o·gy · IPA /ˌnænoʊtɛkˈnɑləd͡ʒi/ 01 n. The manipulation or construction of objects with sizes in the nanometer range or smaller. 1. The manipulation or construction of objects with sizes in the nanometer range or smaller.