Entry 1 sense Webster, 1913 Mitotic /mītˌ-ôt'-ĭk/ · Mi·tot·ic · IPA /maɪˈtɒtɪk/ 01 a. Of or pertaining to mitosis; karyokinetic; as, mitotic cell division; -- opposed to amitotic. 1. Of or pertaining to mitosis; karyokinetic; as, mitotic cell division; -- opposed to amitotic.(Biol.)