Entry 1 sense Webster, 1913 itself /(ĭt*sĕlf")/ · it·self · IPA /ɪtˈsɛlf/ 01 pron. The neuter reflexive pronoun of It; as, the thing is good in itself; it stands by itself. 1. The neuter reflexive pronoun of It; as, the thing is good in itself; it stands by itself. See: It “Borrowing of foreigners, in itself, makes not the kingdom rich or poor.” — Locke.