Entry 1 sense Webster, 1913 Hyperæsthesia · Hy·per·æs·the·si·a · IPA 01 n. A state of exalted or morbidly increased sensibility of the body, or of a part of it. 1. A state of exalted or morbidly increased sensibility of the body, or of a part of it.(Med. & Physiol.)