Entry 1 sense Webster, 1913 Eftsoon · Eft·soon · IPA 01 adv. Again; anew; a second time; at once; speedily. 1. Again; anew; a second time; at once; speedily.[Archaic] “And, if he fall from his capel [horse] eftsone.” — Chaucer. “The champion stout eftsoons dismounted.” — Spenser.