01 a. With nerves unstrung; weak.
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1.
With nerves unstrung; weak.[Obs.]
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2.
Loosed from restraint; recklessly abandoned to sensual pleasures; esp., loose in morals and conduct; profligate; wanton; lewd; debauched.
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3.
Engaging in excessive drinking, or promiscuous sexual activity.
Syn.
Uncurbed; unbridled; disorderly; unrestrained; reckless; wild; wanton; vicious; lax; licentious; lewd; rakish; debauched; profligate.