Entry 1 sense Webster, 1913 Disenfranchise /dĭs-ĭn-frăn'-chīzˌ/ · Dis·en·fran·chise · IPA /ˌdɪs.ɪnˈfɹæn.t͡ʃaɪz/ 01 v. t. To disfranchise; to deprive of the rights of a citizen. 1. To disfranchise; to deprive of the rights of a citizen.