Entry 1 sense Webster, 1913 Contraindication · Con·tra·in·di·ca·tion · IPA /ˌkɒntɹə.ɪndɪˈkeɪʃən/ 01 n. An indication or symptom which forbids the method of treatment usual in such cases. 1. An indication or symptom which forbids the method of treatment usual in such cases.(med.)