Entry 1 sense Webster, 1913 Bloodthirsty /blŭd'-thẽrsˌ-tē/ · Blood·thirst·y · IPA /ˈblʌdˌθɚsti/ 01 a. Eager to shed blood; cruel; sanguinary; murderous; having a bloodlust. 1. Eager to shed blood; cruel; sanguinary; murderous; having a bloodlust.