Entry 1 sense Webster, 1913 Acclimatization /(ăk`klī"mȧ*tĭ*zā"shŭn)/ · Ac·cli·ma·ti·za·tion · IPA /əˌklaɪ.mə.təˈzeɪ.ʃən/ 01 n. The act of acclimatizing; the process of inuring to a new climate, or the state of being so inured. 1. The act of acclimatizing; the process of inuring to a new climate, or the state of being so inured.